The patient is a French man who lives in Senegal and flew back from France on Feb. 26, Health Minister Abdoulaye Diouf Sarr told reporters.
The patient had since been in contact with his wife and two children and is now under quarantine in a hospital in the capital Dakar.
The rapid spread of the new coronavirus has increased fears of a pandemic, prompting governments to step up control measures and sending global markets into a dive.
As of Monday, there have been over 89,000 cases of the virus globally, the majority in China, according to a Reuters tally.
Outside of China, it has spread to 66 countries, with more than 8,800 cases and 130 deaths. Globally, the illness has killed over 3,000 people.